p-PI3 Kinase p85 alpha (Y607) Ab
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p-PI3 Kinase p85 alpha (Y607) Ab
Western blot analysis of extracts from rat kidney cells, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab

产品简介

产品简介

Catalog No.

CY6427

Source

Rabbit pAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

84 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

GRB1, P85A, PI3-kinase p85-alpha subunit, PI3K, PI3K p85-alpha, Phosphatidylinositol 3-kinase regulatory alpha subunit, PtdIns-3-kinase p85-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PI3 Kinase p85 alpha around the phosphorylation site of Y607

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

引用文献

Oncogenic HPV-induced high expression of ESM1 predicts poor prognosis and regulates aerobic glycolysis in cervical cancer

期刊名称：

iScience

PMID：

38947495

影响因子：

4.6

应用范围：

WB

检测物种：

Human

发表时间：

2024-05-27
Dihydroisotanshinone I regulates ferroptosis via PI3K/AKT pathway to enhance cisplatin sensitivity in lung adenocarcinoma

期刊名称：

JOURNAL OF PHARMACY AND PHARMACOLOGY

PMID：

39045884

影响因子：

2.8

应用范围：

WB

检测物种：

Human

发表时间：

2024-07-23
The resistance to anoikis, mediated by Spp1, and the evasion of immune surveillance facilitate the invasion and metastasis of hepatocellular carcinoma

期刊名称：

APOPTOSIS

PMID：

39066845

影响因子：

6.1

应用范围：

WB

检测物种：

Human

发表时间：

2024-07-27
The processing mechanism of Vinegar-processed Curcumae Rhizome enhances anti hepatic fibrotic effects through regulation of PI3K/Akt/mTOR signaling pathway

期刊名称：

PHYTOMEDICINE

PMID：

39395324

影响因子：

6.7

应用范围：

WB

检测物种：

Rat,Human

发表时间：

2024-09-28

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CY6427

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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