p-PI3 Kinase p85 alpha (Y607) Ab
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p-PI3 Kinase p85 alpha (Y607) Ab
Western blot analysis of extracts from rat kidney cells, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab

产品简介

产品简介

Catalog No.

CY6427

Source

Rabbit pAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

84 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

GRB1, P85A, PI3-kinase p85-alpha subunit, PI3K, PI3K p85-alpha, Phosphatidylinositol 3-kinase regulatory alpha subunit, PtdIns-3-kinase p85-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PI3 Kinase p85 alpha around the phosphorylation site of Y607

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

引用文献

LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

PMID：

29282102

影响因子：

5.189

应用范围：

WB

检测物种：

Human

发表时间：

2017-12-28
Electro-acupuncture attenuates the mice premature ovarian failure via mediating PI3K/AKT/mTOR pathway

期刊名称：

LIFE SCIENCES

PMID：

30521869

影响因子：

3.234

应用范围：

WB

检测物种：

Mouse

发表时间：

2018-12-03
Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

31918283

影响因子：

3.743

应用范围：

WB

检测物种：

Human

发表时间：

2019-12-30
Effects of Compound 511 on BDNF-TrkB Signaling in the Mice Ventral Tegmental Area in Morphine-Induced Conditioned Place Preference

期刊名称：

CELLULAR AND MOLECULAR NEUROBIOLOGY

PMID：

32323150

影响因子：

3.606

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-04-22
CircRNA8220 Sponges MiR-8516 to Regulate Cell Viability and Milk Synthesis via Ras/MEK/ERK and PI3K/AKT/mTOR Pathways in Goat Mammary Epithelial Cells

期刊名称：

Animals

PMID：

32759741

影响因子：

2.323

应用范围：

WB

检测物种：

Goat

发表时间：

2020-08-04
MicroRNA-26a inhibits wound healing through decreased keratinocytes migration by regulating ITGA5 through PI3K/AKT signaling pathway

期刊名称：

BIOSCIENCE REPORTS

PMID：

32955094

影响因子：

2.942

应用范围：

WB

检测物种：

Human

发表时间：

2020-09-29

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CY6427

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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