p-PI3 Kinase p85 alpha (Y607) Ab
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p-PI3 Kinase p85 alpha (Y607) Ab
Western blot analysis of extracts from rat kidney cells, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab

产品简介

产品简介

Catalog No.

CY6427

Source

Rabbit pAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

84 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

GRB1, P85A, PI3-kinase p85-alpha subunit, PI3K, PI3K p85-alpha, Phosphatidylinositol 3-kinase regulatory alpha subunit, PtdIns-3-kinase p85-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PI3 Kinase p85 alpha around the phosphorylation site of Y607

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

引用文献

Cannabidiol-dihydroartemisinin conjugates for ameliorating neuroinflammation with reduced cytotoxicity

期刊名称：

BIOORGANIC & MEDICINAL CHEMISTRY

PMID：

33852975

影响因子：

3.641

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-04-02
Melatonin inhibits gallbladder cancer cell migration and invasion via ERK‑mediated induction of epithelial‑to‑mesenchymal transition

期刊名称：

Oncology Letters

PMID：

34188711

影响因子：

2.967

应用范围：

WB

检测物种：

Human

发表时间：

2021-06-15
A novel lncRNA ROPM-mediated lipid metabolism governs breast cancer stem cell properties

期刊名称：

Journal of Hematology & Oncology

PMID：

34715882

影响因子：

17.388

应用范围：

WB

检测物种：

Human

发表时间：

2021-10-29
Knockdown of DEAD-box 51 inhibits tumor growth of esophageal squamous cell carcinoma via the PI3K/AKT pathway

期刊名称：

WORLD JOURNAL OF GASTROENTEROLOGY

PMID：

35125830

影响因子：

5.374

应用范围：

WB

检测物种：

Human

发表时间：

2022-01-28
Shexiang Tongxin Dropping Pills Promote Macrophage Polarization-Induced Angiogenesis Against Coronary Microvascular Dysfunction via PI3K/Akt/mTORC1 Pathway

期刊名称：

Frontiers in Pharmacology

PMID：

35401214

影响因子：

5.988

应用范围：

ICC/IF,WB

检测物种：

Rat,Human

发表时间：

2022-03-23
Compound 511 ameliorates MRSA-induced lung injury by attenuating morphine-induced immunosuppression in mice via PI3K/AKT/mTOR pathway

期刊名称：

PHYTOMEDICINE

PMID：

36252465

影响因子：

6.656

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-09-25

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CY6427

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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