p-PI3 Kinase p85 alpha (Y607) Ab
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p-PI3 Kinase p85 alpha (Y607) Ab
Western blot analysis of extracts from rat kidney cells, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PI3-kinase p85- alpha (Phospho-Tyr607) antibody.
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab
p-PI3 Kinase p85 alpha (Y607) Ab

产品简介

产品简介

Catalog No.

CY6427

Source

Rabbit pAb

UniProt ID

P27986

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

84 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

GRB1, P85A, PI3-kinase p85-alpha subunit, PI3K, PI3K p85-alpha, Phosphatidylinositol 3-kinase regulatory alpha subunit, PtdIns-3-kinase p85-alpha;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PI3 Kinase p85 alpha around the phosphorylation site of Y607

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

引用文献

引用文献

Long Non-Coding RNA uc003jox.1 Promotes Keloid Fibroblast Proliferation and Invasion Through Activating the PI3K/AKT Signaling Pathway

期刊名称：

JOURNAL OF CRANIOFACIAL SURGERY

PMID：

36730437

影响因子：

0.9

应用范围：

WB

检测物种：

Human

发表时间：

2023-04-01
Unveiling the potential mechanisms of Amomi fructus against gastric ulcers via integrating network pharmacology and in vivo experiments

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

37777029

影响因子：

5.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-09-29
Sophoridine Counteracts Obesity via Src-Mediated Inhibition of VEGFR Expression and PI3K/AKT Phosphorylation

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

PMID：

38279206

影响因子：

4.9

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-01-19
Single-cell transcriptomic Atlas of aging macaque ocular outflow tissues

期刊名称：

Protein & Cell

PMID：

38366188

影响因子：

13.6

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2024-02-15
IL-1β promotes esophageal squamous cell carcinoma growth and metastasis through FOXO3A by activating the PI3K/AKT pathway

期刊名称：

Cell Death Discovery

PMID：

38762529

影响因子：

6.1

应用范围：

WB,IHC

检测物种：

Mouse,Human

发表时间：

2024-05-18
Bioactive compounds from Dichloromethane extract of Artemisia rupestris L. alleviates CCl4/ConA-induced acute liver injury by inhibiting PI3K-AKT pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

38848975

影响因子：

4.8

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-06-06

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CY6427

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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