p-STAT3 (Y705) Ab - 上海埃必威生物技术有限公司

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p-STAT3 (Y705) Ab

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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.

Western blot analysis of Phospho-STAT3 (Tyr705) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with IFN-a.

Triptolide delays disease progression in an adult rat model of polycystic kidney disease through the JAK2/STAT3 pathway. -American Journal of Physiology-Renal Physiology

Intracellular Ca2+ homeostasis and JAK1/STAT3 pathway are involved in the protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis. -plos one

All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

Immunohistochemical analysis of paraffin-embedded human pancreas, using Phospho-STAT3 (Y705) Antibody.

Immunofluorescent analysis of HeLa cells treated with IFN-alpha, using Phospho-STAT3 (Y705) Antibody.

产品简介

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产品简介

Catalog No.

CY6566

Source

Recombinant Rabbit mAb

UniProt ID

P40763

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

88 kDa

Observed Mol Weight

88 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

APRF; Stat3; HIES; Acute-phase response factor;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human STAT3 around the phosphorylation site of Y705

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors.Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene.May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

引用文献

Intracellular Ca2+ homeostasis and JAK1/STAT3 pathway are involved in the protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis

期刊名称：

PLoS One

PMID：

28542400

影响因子：

2.806

应用范围：

检测物种：

Mouse

发表时间：

2017-05-23

Triptolide delays disease progression in an adult rat model of polycystic kidney disease through the JAK2-STAT3 pathway

期刊名称：

AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY

PMID：

29513074

影响因子：

3.164

应用范围：

IHC

检测物种：

Rat

发表时间：

2018-08-22

The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement

期刊名称：

Reproductive Biology and Endocrinology

PMID：

29728128

影响因子：

2.852

应用范围：

IHC,WB

检测物种：

Mouse

发表时间：

2018-05-04

PRMT2 links histone H3R8 asymmetric dimethylation to oncogenic activation and tumorigenesis of glioblastoma

期刊名称：

Nature Communications

PMID：

30382083

影响因子：

12.353

应用范围：

检测物种：

Human

发表时间：

2018-10-31

Inhibition of gastric cancer cell apoptosis by long noncoding RNA TRPM2-AS via mitogen-activated protein kinase and activators of transduction-3

期刊名称：

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

PMID：

32424838

影响因子：

3.437

应用范围：

检测物种：

Human

发表时间：

2020-05-18

Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1

期刊名称：

CELL DEATH AND DIFFERENTIATION

PMID：

34853447

影响因子：

15.828

应用范围：

检测物种：

Mouse

发表时间：

2021-12-01

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CY6566

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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