p-STAT3 (Y705) Ab - 上海埃必威生物技术有限公司

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p-STAT3 (Y705) Ab

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All lanes use the Antibody at 1:3K dilution for 1 hour at room temperature.

Western blot analysis of Phospho-STAT3 (Tyr705) expression in (1) HeLa cell lysate; (2) HeLa cell lysate treated with IFN-a.

Triptolide delays disease progression in an adult rat model of polycystic kidney disease through the JAK2/STAT3 pathway. -American Journal of Physiology-Renal Physiology

Intracellular Ca2+ homeostasis and JAK1/STAT3 pathway are involved in the protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis. -plos one

All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

Immunohistochemical analysis of paraffin-embedded human pancreas, using Phospho-STAT3 (Y705) Antibody.

Immunofluorescent analysis of HeLa cells treated with IFN-alpha, using Phospho-STAT3 (Y705) Antibody.

产品简介

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产品简介

Catalog No.

CY6566

Source

Recombinant Rabbit mAb

UniProt ID

P40763

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

88 kDa

Observed Mol Weight

88 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

APRF; Stat3; HIES; Acute-phase response factor;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human STAT3 around the phosphorylation site of Y705

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors.Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene.May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

引用文献

Exposure to short-chain chlorinated paraffins induces astrocyte activation via JAK2/STAT3 signaling pathway

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

36375367

影响因子：

7.129

应用范围：

IHC,WB

检测物种：

Mouse,Rat

发表时间：

2022-11-11

LncGMDS-AS1 promotes the tumorigenesis of colorectal cancer through HuR-STAT3/Wnt axis

期刊名称：

Cell Death & Disease

PMID：

36849492

影响因子：

应用范围：

检测物种：

Human

发表时间：

2023-02-27

S-allylmercaptocysteine promotes anti-tumor immunity by suppressing PD-L1 expression

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

37002570

影响因子：

7.5

应用范围：

检测物种：

Human

发表时间：

2023-03-01

MG53/GMs/HA-Dex neural scaffold promotes the functional recovery of spinal cord injury by alleviating neuroinflammation

期刊名称：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PMID：

38615859

影响因子：

7.7

应用范围：

ICC/IF,WB

检测物种：

Mouse

发表时间：

2024-04-13

Niclosamide modulates phenotypic switch and inflammatory responses in human pulmonary arterial smooth muscle cells

期刊名称：

MOLECULAR AND CELLULAR BIOCHEMISTRY

PMID：

38980591

影响因子：

3.5

应用范围：

检测物种：

Human

发表时间：

2024-07-09

Fisetin Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglia/Macrophage M1 Polarization and JAK2/STAT3 Signaling Pathway

期刊名称：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

PMID：

39096281

影响因子：

5.7

应用范围：

ICC/IF

检测物种：

Mouse

发表时间：

2024-08-03

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CY6566

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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