LC3B Ab - 上海埃必威生物技术有限公司

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LC3B Ab

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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Western blot analysis of LC3B expression in (1) Human brain lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.

SIRT 5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer. -Molecular Oncology

Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

产品简介

引用文献

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产品简介

Catalog No.

CY5992

Source

Recombinant Rabbit mAb

UniProt ID

Q9GZQ8

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

15 kDa

Observed Mol Weight

14, 16 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

ATG8F; LC3B; MAP1LC3B; MLP3B; MAP1LC3B;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human LC3B

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles.Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria.

引用文献

SIRT5-mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer

期刊名称：

Molecular Oncology

PMID：

30443978

影响因子：

5.264

应用范围：

IHC

检测物种：

Mouse

发表时间：

2018-11-15

Size-adjustable micelles co-loaded with a chemotherapeutic agent and an autophagy inhibitor for enhancing cancer treatment via increased tumor retention

期刊名称：

Acta Biomaterialia

PMID：

30878446

影响因子：

6.638

应用范围：

检测物种：

Mouse

发表时间：

2019-03-14

Synergistic cytotoxicity and co-autophagy inhibition in pancreatic tumor cells and cancer-associated fibroblasts by dual functional peptide-modified liposomes

期刊名称：

Acta Biomaterialia

PMID：

31499197

影响因子：

6.638

应用范围：

检测物种：

Mouse,Human

发表时间：

2019-09-06

Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

期刊名称：

BIOMEDICINE & PHARMACOTHERAPY

PMID：

31918283

影响因子：

3.743

应用范围：

检测物种：

Human

发表时间：

2019-12-30

Phenols fragment of Veronica ciliata Fisch. ameliorate free radical-induced nonalcoholic fatty liver disease by mediating PI3K/Akt signaling pathway

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

31978521

影响因子：

3.69

应用范围：

检测物种：

Rat

发表时间：

2020-01-21

Impaired autophagic flux contributes to muscle atrophy in obesity by affecting muscle degradation and regeneration

期刊名称：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PMID：

32102751

影响因子：

2.985

应用范围：

WB,ICC/IF

检测物种：

Mouse,Rat

发表时间：

2020-02-24

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CY5992

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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