LC3B Ab - 上海埃必威生物技术有限公司

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LC3B Ab

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All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.

Western blot analysis of LC3B expression in (1) Human brain lysate; (2) RAW 264.7 cell lysate; (3) C6 cell lysate.

SIRT 5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer. -Molecular Oncology

Prostaglandin E1 Inhibited Diabetes-Induced Phenotypic Switching of Vascular Smooth Muscle Cells Through Activating Autophagy. -Cellular Physiology and Biochemistry

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.

产品简介

引用文献

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产品简介

Catalog No.

CY5992

Source

Recombinant Rabbit mAb

UniProt ID

Q9GZQ8

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

15 kDa

Observed Mol Weight

14, 16 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

ATG8F; LC3B; MAP1LC3B; MLP3B; MAP1LC3B;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human LC3B

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Purification

Affinity-chromatography

Concentration

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Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles.Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria.

引用文献

Curcin C inhibit osteosarcoma cell line U2OS proliferation by ROS induced apoptosis, autophagy and cell cycle arrest through activating JNK signal pathway

期刊名称：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

PMID：

34896468

影响因子：

6.953

应用范围：

检测物种：

Human

发表时间：

2021-12-09

Neospora caninum infection activated autophagy of caprine endometrial epithelial cells via mTOR signaling

期刊名称：

VETERINARY PARASITOLOGY

PMID：

35272252

影响因子：

2.821

应用范围：

WB,ICC/IF

检测物种：

Goat

发表时间：

2022-03-04

A neutrophil-mediated carrier regulates tumor stemness by inhibiting autophagy to prevent postoperative triple-negative breast cancer recurrence and metastasis

期刊名称：

Acta Biomaterialia

PMID：

35447368

影响因子：

10.633

应用范围：

检测物种：

Mouse

发表时间：

2022-04-18

Polystyrene microplastics induce mitochondrial damage in mouse GC-2 cells

期刊名称：

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

PMID：

35489138

影响因子：

7.129

应用范围：

检测物种：

Mouse

发表时间：

2022-04-27

C-reactive protein inhibits C3a/C3aR-dependent podocyte autophagy in favor of diabetic kidney disease

期刊名称：

FASEB JOURNAL

PMID：

35503088

影响因子：

5.834

应用范围：

ICC/IF,WB

检测物种：

Rat,Mouse

发表时间：

2022-05-03

6‑Gingerol suppresses cell viability, migration and invasion via inhibiting EMT, and inducing autophagy and ferroptosis in LPS‑stimulated and LPS‑unstimulated prostate cancer cells

期刊名称：

Oncology Letters

PMID：

35527779

影响因子：

3.111

应用范围：

检测物种：

Human

发表时间：

2022-04-26

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CY5992

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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