Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF

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Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
SDS- PAGE analysis of recombinant mouse M-CSF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF
Recombinant M-CSF (Macrophage colony-stimulating factor), Mouse, AF

产品简介

产品简介

Catalog No.

PY2582

Source

Mouse Cytokines

UniProt ID

Reactivity

Measure by its ability to induce proliferation in NFS-60 cells. The ED50 for this effect is <2 ng/mL. The specific activity of recombinant mouse M-CSF is approximately >5 x 105 IU/mg.

Application

Cell culture, Elisa

Calculated Mol Weight

19 kDa

Observed Mol Weight

17-25 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

CSF-1, MGI-IM

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

Macrophage Colony-Stimulating Factor (M-CSF), is a secreted cytokine which causes hematopoietic stem cells to differentiate into macrophages or other related cell types. The active form of M-CSF/CSF-1 is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF/CSF-1 induces cells of the monocyte/macrophage lineage. It also plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. Upregulation of M-CSF/CSF-1 in the infarcted myocardium may have an active role in healing not only through its effects on cells of monocyte/macrophage lineage, but also by regulating endothelial cell chemokine expression.

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PY2582

规格:

5μg, 20μg, 100μg, 500μg, 1mg

价格:

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期:

3-4天

订购信息:

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