Recombinant FasL (Fas ligand), Mouse, AF
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Recombinant FasL (Fas ligand), Mouse, AF
SDS- PAGE analysis of recombinant mouse FasL
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF
Recombinant FasL (Fas ligand), Mouse, AF

产品简介

产品简介

Catalog No.

PY2527

Source

Mouse Cytokines

UniProt ID

P41047

Reactivity

Measure by its ability to induce apoptosis in Jurkat cells. The ED50 for this effect is <1 μg /mL.

Application

Cell culture, Elisa

Calculated Mol Weight

18 kDa

Observed Mol Weight

17-25 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

soluble Fas Ligand (sFasL), TNFSF6, CD95L, Apo I Ligand, APTL, APT1LG1, CD178, Fas-Lg, Tnfs, Tnlg1a, gld

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the N-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

FasL is a member of the TNF superfamily, and is mainly expressed on the cell surface of activated T cells. FasL induces apoptosis in Fas-bearing cells by binding to Fas Receptor. FasL has the ability to leads to down-regulation of the immune response through killing T cells and activated B cells. The mechanism of Fas-induced apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD, followed by processing of the pro-enzyme into active forms. These active caspases then cleave various cellular substrates, leading to the eventual cell death.

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PY2527

规格：

5μg, 20μg, 100μg, 500μg, 1mg

价格：

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期：

3-4天

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