Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
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Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
SDS- PAGE analysis of recombinant mouse CXCL12
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF
Recombinant CXCL12 (C-X-C motif chemokine 12), Mouse, AF

产品简介

产品简介

Catalog No.

PY2517

Source

Mouse Cytokines

UniProt ID

P40224

Reactivity

Measure by its ability to chemoattract BaF3 cells transfected with human CXCR4. The ED50 for this effect is <0.5 ng/mL.

Application

Cell culture, Elisa

Calculated Mol Weight

9 kDa

Observed Mol Weight

11 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

PB, PBSF/SD, Pbsf, SDF-, Scyb1, Scyb12, Sdf, Sdf1, TLS, TP, Tlsf, Tpar1

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

The stromal cell-derived factor 1 (SDF1), also known as C-X-C motif chemokine 12 (CXCL12), is a chemokine protein that in humans is encoded by the CXCL12 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types. Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the chemokine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The chemokines are characterized by the presence of 4 conserved cysteines that form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, the cysteine residues are adjacent to each other. In the CXC subfamily, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group. CXCL12 signaling has been observed in several cancers. The CXCL12 gene also contains one of 27 SNPs associated with increased risk of coronary artery disease.

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PY2517

规格：

5μg, 20μg, 100μg, 500μg, 1mg

价格：

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期：

3-4天

订购信息：

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