Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
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Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
SDS- PAGE analysis of recombinant human TGF beta 3
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF
Recombinant TGF beta 3 (Transforming growth factor beta 3), Human, AF

产品简介

产品简介

Catalog No.

PY2272

Source

Human Cytokines

UniProt ID

P10600

Reactivity

Measure by its ability to inhibit IL-4-induce proliferation in HT-2 cells. The ED50 for this effect is <50 pg/mL. The specific activity of recombinant human TGF beta 3 is > 2 x 107 IU/mg.

Application

Cell culture, Elisa

Calculated Mol Weight

14 kDa

Observed Mol Weight

13 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. In some experiments, it recommends to add 10 mM HCl when reconstitute lyophilized protein.

Alternative Names

ARVD, ARVD1, LDS5, RNHF, TGFB3, TGF-B3

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

Transforming growth factor-beta 3 (TGF-β3), also named TGFB3, is a member of the TGF beta family of growth factors together with TGF-β1 and -2. TGFB3 is produced as a complex with LAP. This latent form of TGFB3 can be stimulated upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset of integrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 take part in the process such as cell differentiation, embryogenesis and development. In addition, it is found to regulate molecular elements involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development.

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PY2272

规格：

5μg, 20μg, 100μg, 500μg, 1mg

价格：

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期：

3-4天

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