Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF

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Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
SDS- PAGE analysis of recombinant human RANKL
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF
Recombinant RANKL (Receptor activator of nuclear factor kappa-Β ligand), Human, AF

产品简介

产品简介

Catalog No.

PY2265

Source

Human Cytokines

UniProt ID

Reactivity

Measure by its ability to induce osteoclast differentiation in RAW264.7 cells. The ED50 for this effect is <10 ng/mL.

Application

Cell culture, Elisa

Calculated Mol Weight

21 kDa

Observed Mol Weight

17 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

soluble Receptor Activator of NF-kB Ligand, TNFSF11, TRANCE (TNF-Related Activation-induced Cytokine), OPGL, ODF (Osteoclast Differentiation Factor), CD254,sRNAK Ligand

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

RANKL and RANK are members of the TNF superfamily of ligands and receptors that is critical for the regulation of specific immunity and bone turnover. RANK receptor was originally identified as a dendritic cell-membrane protein, which, by interacting with RANKL, augments the ability of dendritic cells. These dendritic cells then stimulate naïve T-cell proliferation in a mixed lymphocyte reaction, promote the survival of RANK+ T-cells, and regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells, including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG.

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PY2265

规格:

5μg, 20μg, 100μg, 500μg, 1mg

价格:

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期:

3-4天

订购信息:

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