Recombinant Noggin, Human, AF

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Recombinant Noggin, Human, AF
SDS- PAGE analysis of recombinant human Noggin
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF
Recombinant Noggin, Human, AF

产品简介

产品简介

Catalog No.

PY2260

Source

Human Cytokines

UniProt ID

Reactivity

Measure by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is <0.05 μg/mL in the presence of 50 ng/mL of recombinant human BMP-4.

Application

Cell culture, Elisa

Calculated Mol Weight

24 kDa

Observed Mol Weight

27 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

NOG, Noggin, SYM1, symphalangism 1 (proximal), synostoses (multiple) syndrome 1, SYNS1, SYNS1A

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

Noggin is a bioactive protein intended for use in cell culture applications. Noggin protein which binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures.

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PY2260

规格:

5μg, 20μg, 100μg, 500μg, 1mg

价格:

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期:

3-4天

订购信息:

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