Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
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Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
SDS- PAGE analysis of recombinant human IL-36RA
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF
Recombinant IL-36RA (Interleukin-36 receptor antagonist), Human, AF

产品简介

产品简介

Catalog No.

PY2242

Source

Human Cytokines

UniProt ID

Q9UBH0

Reactivity

Measure by its ability to inhibit IL-36 gamma-induced IL-8 secretion in PBMC cells. The ED50 for this effect is <2 ng/mL in the presence of 500 ng/mL of recombinant human IL-36 gamma.

Application

Cell culture, Elisa

Calculated Mol Weight

18 kDa

Observed Mol Weight

17 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

FIL1 delta, IL-1F5, IL-1HY1, IL-1L1, IL-1RP3, IL-1ra Homolog 1, IL-1 delta

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

As a result of the interaction of IL-36 ligands with the IL-1Rrp2 receptor. Various activities including dendritic cell maturation and activation are induced. IL-36RA can antagonize the NF-κB signaling through binding to the IL-1Rrp2 receptor by either IL-36α, β or γ in a way of preventing the initiation of functional signaling.

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PY2242

规格：

5μg, 20μg, 100μg, 500μg, 1mg

价格：

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期：

3-4天

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