Recombinant IL-25 (Interleukin-25), Human, AF

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Recombinant IL-25 (Interleukin-25), Human, AF
SDS- PAGE analysis of recombinant human IL-25
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF
Recombinant IL-25 (Interleukin-25), Human, AF

产品简介

产品简介

Catalog No.

PY2227

Source

Human Cytokines

UniProt ID

Reactivity

Measure by its ability to induce IL-8 secretion in human PBMCs. The ED50 for this effect is <5 ng/mL. Measure by its ability to induce CXCL1 secretion in HT29 cells. The ED50 for this effect is <1 ng/mL.

Application

Cell culture, Elisa

Calculated Mol Weight

18 kDa

Observed Mol Weight

19 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

IL17E

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

Interleukin-25 (IL-25) is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. IL-25 is a member of the IL-17 family of cytokines. However, unlike the other members of this family, IL-25 promotes T helper (Th) 2 responses. IL-25 also regulates the development of autoimmune inflammation mediated by IL-17–producing T cells. IL-25 and IL-17, being members of the same cytokine family, play opposing roles in the pathogenesis of organ-specific autoimmunity.

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PY2227

规格:

5μg, 20μg, 100μg, 500μg, 1mg

价格:

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期:

3-4天

订购信息:

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