Recombinant IL-13 (Interleukin-13), Human, AF

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Recombinant IL-13 (Interleukin-13), Human, AF
SDS- PAGE analysis of recombinant human IL-13
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF
Recombinant IL-13 (Interleukin-13), Human, AF

产品简介

产品简介

Catalog No.

PY2211

Source

Human Cytokines

UniProt ID

Reactivity

Measure by its ability to induce TF-1 cells proliferation. The ED50 for this effect is<0.8 ng/mL. The specific activity of recombinant human IL-13 is approximately >1 x106 IU/ mg.

Application

Cell culture, Elisa

Calculated Mol Weight

13 kDa

Observed Mol Weight

15 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

NC30

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>95% as determined by SDS-PAGE. Ni-NTA chromatography.

Concentration

Buffer System

<0.01 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located on chromosome 5q31 with a length of 1.4kb. It has a mass of 13 kDa and folds into 4 alpha helical bundles. The secondary structural features of IL-13 are similar to that of Interleukin 4 (IL-4); however it only has 25% sequence homology to IL-4 and is capable of IL-4 independent signaling. IL-13 is a cytokine secreted by T helper type 2 (Th2) cells, CD4 cells, Natural killer T cell, Mast cell, Basophil cells, Eosinophil cells and Nuocyte cells. Interleukin-13 is a central regulator in IgE synthesis, goblet cell hyperplasia, mucus hypersecretion, airway hyperresponsiveness, fibrosis and chitinase up-regulation. It is a mediator of allergic inflammation and different diseases including asthma.

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PY2211

规格:

5μg, 20μg, 100μg, 500μg, 1mg

价格:

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期:

3-4天

订购信息:

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