Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
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Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
SDS- PAGE analysis of recombinant human IFN beta 1a
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF
Recombinant IFN beta 1a (Interferon beta 1a), Human, AF

产品简介

产品简介

Catalog No.

PY2198

Source

Human Cytokines

UniProt ID

P01574

Reactivity

Measure by its ability to induce apoptosis in HeLa cells. The ED50 for this effect is <15 ng/mL. Measure by its ability to induce cytotoxicity in TF-1 cells. The ED50 for this effect is <0.1 ng/mL. The specific activity of recombinant human IFN beta 1a is approximately >1 x107 IU/ mg.

Application

Cell culture, Elisa

Calculated Mol Weight

21 kDa

Observed Mol Weight

15 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

IFNB1, Type I Interferon

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 8.0.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

Interferon-beta is, a cytokine, released by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. IFN beta 1a conducts through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice are easier to suffer from experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS).In addition, IFN-beta has been proved to suppress the Th17 cell response in both MS and EAE and is usually used to treat MS disease.

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PY2198

规格：

5μg, 20μg, 100μg, 500μg, 1mg

价格：

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期：

3-4天

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