Recombinant HMGB1, Human (Mammalian cell expression), AF
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Recombinant HMGB1, Human (Mammalian cell expression), AF
SDS- PAGE analysis of recombinant human HMGB1
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF
Recombinant HMGB1, Human (Mammalian cell expression), AF

产品简介

产品简介

Catalog No.

PY2194

Source

Human Cytokines

UniProt ID

P09429

Reactivity

Measure by its ability to induce TNF alpha in RAW264.7 cells. The ED50 for this effect is <10 μg/mL.

Application

Cell culture, Elisa

Calculated Mol Weight

36 kDa

Observed Mol Weight

待补充

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

HMG-1, HMG1, HMG3, SBP-1

Host

HEK293

Isotype

Clonality

Modification

His-SUMO tag at the N-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

HMGB1 is present in the nuclei (chromatin associated) and cytoplasm of all cells and is a highly conserved protein in variety of species that. In the cytoplasm, HMGB1 is a regulator of autophagy, enhances cell survival, and limits apoptosis. It also can reduces protein aggregation caused by heat or chemical stress. HMGB1 is released to the extracellular milieu by inflammatory cells and by necrotic and apoptotic cells. Once released, it works as an inflammatory cytokine.HMGB1 is also secreted by macrophages and monocytes as a late response to LPS, TNF-α, IL-1β, or IFN-γ.

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PY2194

规格：

5μg, 20μg, 100μg, 500μg, 1mg

价格：

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期：

3-4天

订购信息：

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