Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF

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Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
SDS- PAGE analysis of recombinant human CCL4
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF
Recombinant CCL4 (C-C motif chemokine ligand 4), Human, AF

产品简介

产品简介

Catalog No.

PY2126

Source

Human Cytokines

UniProt ID

Reactivity

Measure by its ability to chemoattract BaF3 cells transfected with human CCR5. The ED50 for this effect is <10 ng/mL.

Application

Cell culture, Elisa

Calculated Mol Weight

8 kDa

Observed Mol Weight

11 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

MIP-1b: Macrophage Inflammatory Protein-1β, ACT-2

Host

Escherichia coli

Isotype

Clonality

Modification

Tag-free

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 50 mM Tris and 150 mM NaCl, pH 8.5.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

CCL4 act as an important pro-inflammatory cytokine during acute and chronic inflammatory responses. CCL4 also play a role as an attractant NK cells, dendritic cells, monocytes, and lymphocytes to sites of injury and inflammation. As CCL4 conducts signaling through G-protein-coupled receptor CCR5, which is a major co-receptor for M-tropic HIV strains. Thus, binding of CCL4 to CCR5 inhibits HIV entry and reduces the cell surface expression of CCR5. CCL4 has been identified as one of the major anti-HIV factors produced by CD8+ T cells.

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PY2126

规格:

5μg, 20μg, 100μg, 500μg, 1mg

价格:

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期:

3-4天

订购信息:

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