Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
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Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
SDS- PAGE analysis of recombinant human BMP-11
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF
Recombinant BMP-11 (Bone morphogenetic protein-11), Human, AF

产品简介

产品简介

Catalog No.

PY2109

Source

Human Cytokines

UniProt ID

O95390

Reactivity

Measure by its ability to induce alkaline phosphatase production by ATDC5 cells. The ED50 for this effect is <11 ng/mL. Measure by its ability to induce hemoglobin expression in K562 cells. The ED50 for this effect is <4 ng/mL.

Application

Cell culture, Elisa

Calculated Mol Weight

13 kDa

Observed Mol Weight

16 kDa

Recommended Dilution

It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.

Alternative Names

Growth/Differentiation Factor-11, GDF-11

Host

Escherichia coli

Isotype

Clonality

Modification

His-tag at the C-terminus

Immunogen

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Purification

>98% as determined by SDS-PAGE. Ni-NTA chromatography

Concentration

Buffer System

<0.1 EU per 1 μg of the protein by the LAL method. The protein was lyophilized from a 0.2 µm filtered solution containing 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.

Storage Condition

Lyophilized protein should be stored at -20°C for 1 year. Upon reconstitution, store at 2°C to 8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA, 10%FBS, 5%HSA or 5% trehalose solution), protein aliquots should be stored at -20°C or -80°C for 3-6 months.

Description

BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. BMP-11 is a regulator of cell growth and differentiation during muscular and neural development. BMP-11 binds the transforming growth factor-beta receptors ALK4, ALK5, and ALK7 to activate SMAD signaling. In adults, exogenous BMP-11 promotes cardiomyocyte regeneration to reverse age-related cardiac hypertrophy.

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PY2109

规格：

5μg, 20μg, 100μg, 500μg, 1mg

价格：

¥800/5μg, ¥2000/20μg, ¥6000/100μg, ¥18000/500μg, ¥26000/1mg

货期：

3-4天

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