p-WNK1 (T60) Ab
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p-WNK1 (T60) Ab
Western Blot analysis of 293 cells using p-WNK1 (T60) Ab.
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab
p-WNK1 (T60) Ab

产品简介

产品简介

Catalog No.

EY2201

Source

Rabbit pAb

UniProt ID

Q9H4A3

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

251 kDa

Observed Mol Weight

230 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:100-1:200

Alternative Names

WNK1; WNK1; HSN2; KDP; KIAA0344; PRKWNK1; Serine/threonine-protein kinase WNK1; Erythrocyte 65 kDa protein; p65; Kinase deficient protein; Protein kinase lysine-deficient 1; Protein kinase with no lysine 1; hWNK1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human WNK1 around the phosphorylation site of T60

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine-protein kinase component of the WNK1-SPAK/OSR1 kinase cascade, which acts as a key regulator of blood pressure and regulatory volume increase by promoting ion influx.WNK1 mediates regulatory volume increase in response to hyperosmotic stress by acting as a molecular crowding sensor, which senses cell shrinkage and mediates formation of a membraneless compartment by undergoing liquid-liquid phase separation.

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EY2201

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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