p-PDK1 (Y243) Ab
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p-PDK1 (Y243) Ab
U87 cells were stimulated with or without hypoxia for 6 h. Immunoblotting analyses of mitochondrial lysates were performed with the indicated antibodies.
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab
p-PDK1 (Y243) Ab

产品简介

产品简介

Catalog No.

EY2165

Source

Rabbit pAb

UniProt ID

Q15118

Reactivity

Human;Rat

Application

WB

Calculated Mol Weight

49 kDa

Observed Mol Weight

Recommended Dilution

WB 1:500-1:1000

Alternative Names

PDHK1; PDK1; PDH kinase 1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PDK1 around the phosphorylation site of Y243

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.

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EY2165

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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