p-ADAM 17 (T735) Ab
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p-ADAM 17 (T735) Ab
Western blot analysis of extracts from K562 cells treated with UV using p-ADAM 17 (T735) Ab.The lane on the left is treated with the antigen-specific peptide.
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab
p-ADAM 17 (T735) Ab

产品简介

产品简介

Catalog No.

EY2137

Source

Rabbit pAb

UniProt ID

P78536

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

93 kDa

Observed Mol Weight

93 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

ADAM17; CSVP; TACE; NISBD; ADAM18; CD156B

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human ADAM 17 around the phosphorylation site of T735

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

TACE is responsible for the shedding of EGFR ligands such as amphiregulin and TNF-α. Some tumors have hyperactivated EGFR due to upregulated TNF-α production and upregulated TACE, making TACE a potential target for drug development. TACE activates Notch in a ligand-independent manner and has been shown to play a role in the development of the Drosophila nervous system.

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EY2137

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

订购信息：

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