INCENP Ab

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INCENP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
INCENP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
INCENP Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab
INCENP Ab

产品简介

产品简介

Catalog No.

DY2160

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IP;FC

Calculated Mol Weight

105 kDa

Observed Mol Weight

140 kDa

Recommended Dilution

WB 1:1000-1:5000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

Inner centromere protein

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human INCENP

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Acts as a scaffold regulating CPC localization and activity. The C-terminus associates with AURKB or AURKC, the N-terminus associated with BIRC5/survivin and CDCA8/borealin tethers the CPC to the inner centromere, and the microtubule binding activity within the central SAH domain directs AURKB/C toward substrates near microtubules.

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DY2160

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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