SRD5A2 Ab
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SRD5A2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SRD5A2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SRD5A2 Ab
Western blot analysis of SRD5A2 expression in PC3 cell lysate.
SRD5A2 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab
SRD5A2 Ab

产品简介

产品简介

Catalog No.

CY8576

Source

Recombinant Rabbit mAb

UniProt ID

P31213

Reactivity

Human;Rat

Application

WB;IP

Calculated Mol Weight

28 kDa

Observed Mol Weight

28 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

SRD5A2; 5 alpha-SR2; S5AR 2; Type II 5-alpha reductase; SR type 2; Steroid 5-alpha-reductase 2;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SRD5A2

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

引用文献

引用文献

The antiandrogenic effect of neferine, liensinine, and isoliensinine by inhibiting 5-α-reductase and androgen receptor expression via PI3K/AKT signaling pathway in prostate cancer

期刊名称：

PHARMAZIE

PMID：

33964997

影响因子：

1.267

应用范围：

WB

检测物种：

Human

发表时间：

2021-05-01
Sinularin Exerts Anti-cancer Effects by Inducing Oxidative Stress-mediated Ferroptosis, Apoptosis, and Autophagy in Prostate Cancer Cells

期刊名称：

Anti-Cancer Agents in Medicinal Chemistry

PMID：

37005535

影响因子：

2.8

应用范围：

WB

检测物种：

Human

发表时间：

2023-07-01
Neferine attenuates development of testosterone-induced benign prostatic hyperplasia in mice by regulating androgen and TGF-β/Smad signaling pathways

期刊名称：

SAUDI PHARMACEUTICAL JOURNAL

PMID：

37293563

影响因子：

4.1

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-05-11
Capsaicin reduces blood glucose and prevents prostate growth by regulating androgen, RAGE/IGF-1/Akt, TGF-β/Smad signalling pathway and reversing epithelial-mesenchymal transition in streptozotocin-induced diabetic mice

期刊名称：

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

PMID：

38700794

影响因子：

3.1

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-05-03

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CY8576

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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