HIF 1 alpha inhibitor Ab

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HIF 1 alpha inhibitor Ab
Western blot analysis of HIF1AN expression in Jurkat cell lysate.
HIF 1 alpha inhibitor Ab
All lanes use the Antibody at 1:1k dilution for 1 hour at room temperature.
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab
HIF 1 alpha inhibitor Ab

产品简介

产品简介

Catalog No.

CY8421

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

40 kDa

Observed Mol Weight

40 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

FIH 1; FIH1; HIF1AN;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human HIF 1 alpha inhibitor

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins.

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CY8421

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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