TRIM29 Ab

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TRIM29 Ab
Western blot analysis of TRIM29 expression in JAR cell lysate.
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab
TRIM29 Ab

产品简介

产品简介

Catalog No.

CY8412

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

66 kDa

Observed Mol Weight

68 kDa

Recommended Dilution

WB 1:1000-1:2000

Alternative Names

ATDC; TRIM29;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human TRIM29

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.

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CY8412

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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