5 Lipoxygenase Ab
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5 Lipoxygenase Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
5 Lipoxygenase Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
5 Lipoxygenase Ab
Western blot analysis of 5 Lipoxygenase expression in K562 cell lysate.
5 Lipoxygenase Ab
5 Lipoxygenase Ab
5 Lipoxygenase Ab
5 Lipoxygenase Ab
5 Lipoxygenase Ab
5 Lipoxygenase Ab
5 Lipoxygenase Ab
5 Lipoxygenase Ab
5 Lipoxygenase Ab

产品简介

产品简介

Catalog No.

CY8019

Source

Recombinant Rabbit mAb

UniProt ID

P09917

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

78 kDa

Observed Mol Weight

78 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

ALOX5; 5-LO; 5-LOX; 5LPG; LOG5; MGC163204; LOX5; 5-lipoxygenase ; 5 Lipoxygenase; 5 LOX; ALOX 5;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human 5 Lipoxygenase

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Catalyzes the oxygenation of arachidonate ((5Z,8Z,11Z,14Z)-eicosatetraenoate) to 5-hydroperoxyeicosatetraenoate (5-HPETE) followed by the dehydration to 5,6- epoxyeicosatetraenoate (Leukotriene A4/LTA4), the first two steps in the biosynthesis of leukotrienes, which are potent mediators of inflammation.

引用文献

引用文献

Dihydroartemisinin modulated arachidonic acid metabolism and mitigated liver inflammation by inhibiting the activation of 5-LOX and COX-2

期刊名称：

Heliyon

PMID：

39027511

影响因子：

3.4

应用范围：

IHC

检测物种：

Mouse

发表时间：

2024-06-23

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CY8019

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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