p-MLKL (S358) Ab
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p-MLKL (S358) Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
p-MLKL (S358) Ab
Western blot analysis of Phospho-MLKL (S358) expression in (1) HT-29 cell lysate; (2) HT-29 cell lysate treated with TNF alpha+ Smac mimetic+ z-VAD.
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab
p-MLKL (S358) Ab

产品简介

产品简介

Catalog No.

CY7146

Source

Recombinant Rabbit mAb

UniProt ID

Q8NB16

Reactivity

Human

Application

WB;IHC

Calculated Mol Weight

54 kDa

Observed Mol Weight

54 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

Alternative Names

hMLKL; Mlkl;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human MLKL around the phosphorylation site of S358

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage.

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CY7146

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

订购信息：

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