SKP1 Ab

一键复制产品信息

SKP1 Ab
Western blot analysis of Skp1 expression in (1) 293T cell lysate; (2) NIH/3T3 cell lysate.
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab
SKP1 Ab

产品简介

产品简介

Catalog No.

CY7130

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF;FC

Calculated Mol Weight

19 kDa

Observed Mol Weight

19 kDa

Recommended Dilution

WB 1:1000-1:2000

ICC/IF 1:50-1:200

FC 1:20-1:100

Alternative Names

OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human SKP1

点击查询

Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5, CEP68 and probably NFKB2.

引用文献

引用文献

暂无数据

用户反馈

用户反馈

用户评论
用户名:
评论内容:
评论时间:
回复内容:
回复时间:
上一页
下一页
页码:
总页数:
总行数:
首页
尾页
CY7130

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

您可以联系授权经销商购买Abways产品以及获得技术支持,也可以直接联系Abways中国

Click here

>> 针对此靶点的所有抗体产品

>> 针对此靶点的所有兔单抗产品