PHD2 Ab

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PHD2 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
PHD2 Ab
Western blot analysis of PHD2 / prolyl hydroxylase expression in SH-SY5Y cell lysate.
PHD2 Ab
PHD2 Ab
PHD2 Ab
PHD2 Ab
PHD2 Ab
PHD2 Ab
PHD2 Ab
PHD2 Ab
PHD2 Ab
PHD2 Ab

产品简介

产品简介

Catalog No.

CY7001

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human

Application

WB;IP

Calculated Mol Weight

46 kDa

Observed Mol Weight

50 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

EGLN1; C1orf12; ECYT3; HIFPH2; HPH2; PHD2; SM-20; SM20; ZMYND6;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PHD2

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF1B. Hydroxylated HIFs are then targeted for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

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CY7001

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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