MBD1 Ab
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MBD1 Ab
Western blot analysis of MBD1 expression in HeLa cell lysate.
MBD1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
MBD1 Ab
MBD1 Ab
MBD1 Ab
MBD1 Ab
MBD1 Ab
MBD1 Ab
MBD1 Ab
MBD1 Ab
MBD1 Ab
MBD1 Ab

产品简介

产品简介

Catalog No.

CY6941

Source

Recombinant Rabbit mAb

UniProt ID

Q9UIS9

Reactivity

Human

Application

WB;IHC;ICC/IF;IHF;IP

Calculated Mol Weight

67 kDa

Observed Mol Weight

67 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

Alternative Names

CXXC 3; Mbd1; MECP1 COMPLEX; PCM1; RFT;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human MBD1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binding is abolished by the presence of 7-mG that is produced by DNA damage by methylmethanesulfonate (MMS). Acts as transcriptional repressor and plays a role in gene silencing by recruiting ATF7IP, which in turn recruits factors such as the histone methyltransferase SETDB1.

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CY6941

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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