HMGCR Ab
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HMGCR Ab
Western blot analysis of HMGCR expression in Jurkat cell lysate.
HMGCR Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
HMGCR Ab
HMGCR Ab
HMGCR Ab
HMGCR Ab
HMGCR Ab
HMGCR Ab
HMGCR Ab
HMGCR Ab
HMGCR Ab
HMGCR Ab

产品简介

产品简介

Catalog No.

CY6640

Source

Recombinant Rabbit mAb

UniProt ID

P04035

Reactivity

Human;Mouse;Rat

Application

WB;IP

Calculated Mol Weight

97 kDa

Observed Mol Weight

97 kDa

Recommended Dilution

WB 1:1000-1:2000

IP 1:20-1:50

Alternative Names

3H3M; HMDH; HMG CoA reductase; HMG CoAR;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human HMGCR

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.

引用文献

引用文献

Sterol sulfate alleviates atherosclerosis via mediating hepatic cholesterol metabolism in ApoE−/− mice

期刊名称：

Food & Function

PMID：

33977967

影响因子：

5.396

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-04-15

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CY6640

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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