p-ZAP70 (Y493) Ab

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p-ZAP70 (Y493) Ab
Western blot analysis of ZAP-70 phosphorylation expression in Jurkat whole cell lysates.The lane on the left is treated with the antigen-specific peptide.
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab
p-ZAP70 (Y493) Ab

产品简介

产品简介

Catalog No.

CY6565

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

70 kDa

Observed Mol Weight

70 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

70 kDa zeta-associated protein, EC 2.7.10.2, SRK, Syk-related tyrosine kinase, ZA70, ZAP-70, ZAP70, kinase ZAP70

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human ZAP70 around the phosphorylation site of Y493

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif at the plasma membrane.

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CY6565

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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