p-STAT3 (S727) Ab
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p-STAT3 (S727) Ab
Western blot analysis of STAT3 phosphorylation expression in HeLa whole cell lysates.The lane on the left is treated with the antigen-specific peptide.
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab
p-STAT3 (S727) Ab

产品简介

产品简介

Catalog No.

CY6500

Source

Rabbit pAb

UniProt ID

P40763

Reactivity

Human;Mouse;Rat

Application

WB;IHC;IP

Calculated Mol Weight

88 kDa

Observed Mol Weight

86 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

IP 1:20-1:50

Alternative Names

APRF, Acute-phase response factor, Signal transducer and activator of transcription 3

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human STAT3 around the phosphorylation site of S727

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors.Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene.May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.

引用文献

引用文献

Intracellular Ca2+ homeostasis and JAK1/STAT3 pathway are involved in the protective effect of propofol on BV2 microglia against hypoxia-induced inflammation and apoptosis

期刊名称：

PLoS One

PMID：

28542400

影响因子：

2.806

应用范围：

WB

检测物种：

Mouse

发表时间：

2017-05-23
Discovery of a Novel Potent STAT3 Inhibitor HP590 with Dual p-Tyr705/Ser727 Inhibitory Activity for Gastric Cancer Treatment

期刊名称：

JOURNAL OF MEDICINAL CHEMISTRY

PMID：

36103247

影响因子：

8.039

应用范围：

IHC

检测物种：

Mouse

发表时间：

2022-09-14
Discovery of a Highly Potent and Orally Bioavailable STAT3 Dual Phosphorylation Inhibitor for Pancreatic Cancer Treatment

期刊名称：

JOURNAL OF MEDICINAL CHEMISTRY

PMID：

36282975

影响因子：

8.039

应用范围：

IHC

检测物种：

Mouse

发表时间：

2022-10-25
Aqueous M. oleifera leaf extract alleviates DSS-induced colitis in mice through suppression of inflammation

期刊名称：

JOURNAL OF ETHNOPHARMACOLOGY

PMID：

37480965

影响因子：

5.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-07-20
Exploration of novel isoxazole-fused quinone derivatives as anti-colorectal cancer agents through inhibiting STAT3 and elevating ROS level

期刊名称：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

PMID：

38704936

影响因子：

6

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2024-04-30

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CY6500

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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