p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
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p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
Western blot analysis of PI3-kinase p85- alpha/ gamma phosphorylation expression in H2O2 treated COS7 whole cell lysates.The lane on the left is treated with the antigen-specific peptide.
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab
p-PI3 Kinase p85 alpha/gamma (Y467/Y199) Ab

产品简介

产品简介

Catalog No.

CY6428

Source

Rabbit pAb

UniProt ID

P27986/Q92569

Reactivity

Human;Mouse;Rat

Application

WB;ICC/IF

Calculated Mol Weight

84,54 kDa

Observed Mol Weight

54, 83 kDa

Recommended Dilution

WB 1:500-1:1000

ICC/IF 1:50-1:200

Alternative Names

GRB1, P85A, PI3-kinase p85-alpha subunit, PI3K, PI3K p85-alpha, Phosphatidylinositol 3-kinase regulatory alpha subunit, PtdIns-3-kinase p85-alpha; P55G, PI3-kinase p85-gamma subunit, PI3K p85-gamma, Phosphatidylinositol 3-kinase regulatory gamma subunit,

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human PI3 Kinase p85 alpha around the phosphorylation site of Y467

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

PIK3R1 is a regulatory subunit of phosphoinositide-3-kinase. Mediates binding to a subset of tyrosine-phosphorylated proteins through its SH2 domain. Acts as an adapter, mediating the association of the p110 catalytic unit of the alpha, beta and delta enzymes to the plasma membrane, where p110 phosphorylates inositol lipids. May play an additional role in the regulation of the actin cytoskeleton. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

引用文献

引用文献

Upregulation of LRRC8A by m5C modification-mediated mRNA stability suppresses apoptosis and facilitates tumorigenesis in cervical cancer

期刊名称：

International Journal of Biological Sciences

PMID：

36632452

影响因子：

9.2

应用范围：

WB

检测物种：

Human

发表时间：

2023-01-01
Metabolomics combined with network pharmacology reveals a role for astragaloside IV in inhibiting enterovirus 71 replication via PI3K-AKT signaling

期刊名称：

Journal of Translational Medicine

PMID：

38858642

影响因子：

6.1

应用范围：

WB

检测物种：

Human

发表时间：

2024-06-10

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CY6428

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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