p-IRS 1 (S636) Ab
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p-IRS 1 (S636) Ab
Western blot analysis of extracts from 293 cells and COLO205 cells, using IRS-1 (Phospho-Ser636) antibody.
p-IRS 1 (S636) Ab
Immunohistochemistry analysis of paraffin-embedded human brain tissue using IRS-1 (Phospho-Ser636) antibody.
p-IRS 1 (S636) Ab
Immunofluorescence analysis of MCF7 cells, using IRS-1 (Phospho-Ser636) antibody.
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab
p-IRS 1 (S636) Ab

产品简介

产品简介

Catalog No.

CY6308

Source

Rabbit pAb

UniProt ID

P35568

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF

Calculated Mol Weight

132 kDa

Observed Mol Weight

160 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

ICC/IF 1:50-1:200

IHF 1:50-1:100

Alternative Names

IRS-1, IRS1, Insulin receptor substrate-1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human IRS 1 around the phosphorylation site of S636

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.

引用文献

引用文献

Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity

期刊名称：

Animal Nutrition

PMID：

36016966

影响因子：

5.285

应用范围：

WB

检测物种：

Fish

发表时间：

2022-06-24

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CY6308

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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