p-IKK alpha/beta (S176/S177) Ab
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p-IKK alpha/beta (S176/S177) Ab
Western blot analysis of extracts from 3T3 cells, treated with TNF (20ng/ml, 30mins), using IKK- alpha (Phospho-Ser176)/ IKK- beta (Phospho-Ser177) antibody.
p-IKK alpha/beta (S176/S177) Ab
Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using IKK- alpha (Phospho-Ser176)/ IKK- beta (Phospho-Ser177) antibody.
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab
p-IKK alpha/beta (S176/S177) Ab

产品简介

产品简介

Catalog No.

CY6290

Source

Rabbit pAb

UniProt ID

O15111/O14920

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

85,87 kDa

Observed Mol Weight

85 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; IKBKB; IKK-B; IKK-beta; IKK2; IKKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; Inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; Nuclear facto

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human IKK alpha around the phosphorylation site of S176

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses.

引用文献

引用文献

Euphorbia factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation in mice through the suppression of NF-κB activation

期刊名称：

BIOCHEMICAL PHARMACOLOGY

PMID：

30055150

影响因子：

4.235

应用范围：

WB

检测物种：

Mouse

发表时间：

2018-07-26
Euphorbia Factor L2 ameliorates the Progression of K/BxN Serum-Induced Arthritis by Blocking TLR7 Mediated IRAK4/IKKβ/IRF5 and NF-kB Signaling Pathways

期刊名称：

Frontiers in Pharmacology

PMID：

34950033

影响因子：

5.811

应用范围：

WB

检测物种：

Mouse

发表时间：

2021-12-03
Hydroxysafflor yellow A ameliorates alcohol-induced liver injury through PI3K/Akt and STAT3/NF-κB signaling pathways

期刊名称：

PHYTOMEDICINE

PMID：

38878526

影响因子：

6.7

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2024-06-08

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CY6290

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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