p-GSK3 beta (S9) Ab
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p-GSK3 beta (S9) Ab
Western blot analysis of GSK3 beta phosphorylation expression in EGF treated HeLa whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab
p-GSK3 beta (S9) Ab

产品简介

产品简介

Catalog No.

CY6248

Source

Rabbit pAb

UniProt ID

P49841

Reactivity

Human;Mouse;Rat

Application

WB;IHC;IP

Calculated Mol Weight

47 kDa

Observed Mol Weight

46 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

IP 1:20-1:50

Alternative Names

glycogen synthase kinase 3 beta; Glycogen synthase kinase-3 beta; GSK-3 beta; GSK3B; GSK3beta isoform

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human GSK3 beta around the phosphorylation site of S9

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1.Requires primed phosphorylation of the majority of its substrates.

引用文献

引用文献

Benzene metabolite hydroquinone induces apoptosis of bone marrow mononuclear cells through inhibition of β-catenin signaling

期刊名称：

TOXICOLOGY IN VITRO

PMID：

28886972

影响因子：

2.866

应用范围：

WB

检测物种：

Human

发表时间：

2017-09-05
JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/β-catenin/CCND1 signaling

期刊名称：

JOURNAL OF CLINICAL INVESTIGATION

PMID：

29584620

影响因子：

13.251

应用范围：

WB

检测物种：

Human

发表时间：

2018-03-26
Inhibition of pyruvate dehydrogenase kinase improves carbohydrate utilization in Nile tilapia by regulating PDK2/4-PDHE1α axis and insulin sensitivity

期刊名称：

Animal Nutrition

PMID：

36016966

影响因子：

5.285

应用范围：

WB

检测物种：

Fish

发表时间：

2022-06-24
The AMPK and AKT/GSK3β pathways are involved in recombinant proteins fibroblast growth factor 1 (rFGF1 and rFGF1a) improving glycolipid metabolism in rainbow trout (Oncorhynchus mykiss) fed a high carbohydrate diet

期刊名称：

Animal Nutrition

PMID：

38444689

影响因子：

6.1

应用范围：

WB

检测物种：

Fish

发表时间：

2024-01-03

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CY6248

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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