p-ERK1/2 (T202/T185) Ab
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p-ERK1/2 (T202/T185) Ab
Western blot analysis of p44/42 MAP Kinase phosphorylation expression in EGF treated A431 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab
p-ERK1/2 (T202/T185) Ab

产品简介

产品简介

Catalog No.

CY6190

Source

Rabbit pAb

UniProt ID

P27361/P28482

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

43,41 kDa

Observed Mol Weight

43, 41 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

EC 2.7.11.24; ERK-1; ERK1; ERT2; Extracellular signal- regulated kinase 1; Insulin-stimulated MAP2 kinase; kinase ERK1; MAP kinase 1; MAPK 1; MAPK3; Microtubule- associated protein-2 kinase; Mitogen-activated protein kinase 3; MK03; MNK1; p44-ERK1; P44-ER

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human ERK1 around the phosphorylation site of T202

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

引用文献

引用文献

Mesenchymal stem cells maintain the stemness of colon cancer stem cells via interleukin-8/mitogen-activated protein kinase signaling pathway

期刊名称：

EXPERIMENTAL BIOLOGY AND MEDICINE

PMID：

32122165

影响因子：

3.139

应用范围：

WB,IHC

检测物种：

Human

发表时间：

2020-03-02
Decitabine attenuates dextran sodium sulfate‑induced ulcerative colitis through regulation of immune regulatory cells and intestinal barrier

期刊名称：

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

PMID：

32468024

影响因子：

3.098

应用范围：

WB

检测物种：

Mouse

发表时间：

2020-05-18
Up-regulation of CXCL8 expression is associated with a poor prognosis and enhances tumor cell malignant behaviors in liver cancer

期刊名称：

BIOSCIENCE REPORTS

PMID：

32766720

影响因子：

2.942

应用范围：

WB

检测物种：

Human

发表时间：

2020-08-20

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CY6190

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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