p-Protein Eps15 (Y849) Ab
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p-Protein Eps15 (Y849) Ab
Western blot analysis on HepG2 cell lysate using Phospho-EPS15(Tyr849) Antibody
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab
p-Protein Eps15 (Y849) Ab

产品简介

产品简介

Catalog No.

CY6189

Source

Rabbit pAb

UniProt ID

P42566

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

99 kDa

Observed Mol Weight

98 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

AF-1p protein; AF1P; EP15; epidermal growth factor receptor pathway substrate 15 (AF1p); epidermal growth factor receptor substrate 15

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human Protein Eps15 around the phosphorylation site of Y849

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Involved in cell growth regulation. May be involved in the regulation of mitogenic signals and control of cell proliferation. Involved in the internalization of ligand-inducible receptors of the receptor tyrosine kinase (RTK) type, in particular EGFR. Plays a role in the assembly of clathrin-coated pits (CCPs). Acts as a clathrin adapter required for post-Golgi trafficking. Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR);internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.

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CY6189

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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