p-Caspase 9 (T125) Ab
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p-Caspase 9 (T125) Ab
Western blot analysis of extracts from HeLa cells, treated with TNF (20ng/ml, 5mins) and calyculinA (50ng/ml, 15mins), using Caspase 9 (Phospho-Thr125) antibody.
p-Caspase 9 (T125) Ab
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase 9 (Phospho-Thr125) antibody.
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab
p-Caspase 9 (T125) Ab

产品简介

产品简介

Catalog No.

CY6081

Source

Rabbit pAb

UniProt ID

P55211

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

46 kDa

Observed Mol Weight

47 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

APAF-3, Apoptotic protease Mch-6, Apoptotic protease activating factor 3, CASP-9, Caspase-9, Caspase-9 precursor, Caspase9, EC 3.4.22.-, ICE-LAP6, ICE-like apoptotic protease 6, MCH6, RNCASP9

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human Caspase 9 around the phosphorylation site of T125

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

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CY6081

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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