p-ASK1 (S966) Ab

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p-ASK1 (S966) Ab
Western blot analysis of extracts from 293 cells, treated with TNF (20ng/ml, 15mins) and calyculin A (50nM, 15mins), using ASK1 (Phospho-Ser966) antibody.The lane on the left is treated with the antigen-specific peptide.
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab
p-ASK1 (S966) Ab

产品简介

产品简介

Catalog No.

CY6035

Source

Rabbit pAb

UniProt ID

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

155 kDa

Observed Mol Weight

155 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

Apoptosis signal- regulating kinase 1; ASK-1; EC 2.7.11.25; kinase ASK1; M3K5; MAP3K5; MAPK/ERK kinase kinase 5; MAPKKK5; MEK kinase 5; MEKK 5; MEKK5; Mitogen-activated protein kinase kinase kinase 5

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human ASK1 around the phosphorylation site of S966

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival. Plays a crucial role in the apoptosis signal transduction pathway through mitochondria-dependent caspase activation. MAP3K5/ASK1 is required for the innate immune response, which is essential for host defense against a wide range of pathogens.

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CY6035

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

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