p-APC (S2054) Ab

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p-APC (S2054) Ab
Western blot analysis on HuvEc cell lysate using Phospho-APC(Ser2054) Antibody
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab
p-APC (S2054) Ab

产品简介

产品简介

Catalog No.

CY6033

Source

Rabbit pAb

UniProt ID

Reactivity

Human

Application

WB;IHC

Calculated Mol Weight

312 kDa

Observed Mol Weight

311 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

APC, APC protein, Adenomatous polyposis coli protein, DP2.5, mAPC

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human APC around the phosphorylation site of S2054

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Associates with both microtubules and actin filaments, components of the cytoskeleton.

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CY6033

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

次日发货

订购信息:

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