p-AKT1 (T308) Ab
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p-AKT1 (T308) Ab
Western blot analysis of extracts from Jurkat cells, treated with EGF (200ng/ml, 5mins), using AKT1 (Phospho-Thr308) antibody.
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab
p-AKT1 (T308) Ab

产品简介

产品简介

Catalog No.

CY6021

Source

Rabbit pAb

UniProt ID

P31749

Reactivity

Human;Mouse;Rat

Application

WB

Calculated Mol Weight

56 kDa

Observed Mol Weight

56-60 kDa

Recommended Dilution

WB 1:500-1:1000

Alternative Names

AKT, AKT1 kinase, C-AKT, EC 2.7.11.1, PKB, PKB-alpha, Protein kinase B, RAC, RAC-PK-alpha, RAC-alpha serine/threonine kinase, kinase Akt1

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human AKT1 around the phosphorylation site of T308

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.

引用文献

引用文献

JAM3 maintains leukemia-initiating cell self-renewal through LRP5/AKT/β-catenin/CCND1 signaling

期刊名称：

JOURNAL OF CLINICAL INVESTIGATION

PMID：

29584620

影响因子：

13.251

应用范围：

WB

检测物种：

Human

发表时间：

2018-03-26

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CY6021

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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