p-AKT (S473) Ab
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p-AKT (S473) Ab
Western blot analysis of extracts from HeLa cells treated with heat shock, using Akt(Phospho-Ser473) Antibody.
p-AKT (S473) Ab
Immunohistochemical analysis of paraffin- embedded breast carcinoma, using Akt (Phospho-Ser473) Antibody.
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab
p-AKT (S473) Ab

产品简介

产品简介

Catalog No.

CY6016

Source

Rabbit pAb

UniProt ID

P31749/P31751/

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

56 kDa

Observed Mol Weight

56 kDa

Recommended Dilution

WB 1:500-1:1000

IHC 1:50-1:100

Alternative Names

EC 2.7.11.1 RAC-PK-alpha Protein kinase B PKB C-AKT/EC 2.7.11.1 RAC-PK-beta Protein kinase Akt-2 Protein kinase B, beta PKB beta/EC 2.7.11.1 RAC-PK-gamma Protein kinase Akt-3 Protein kinase B, gamma PKB gamma STK-2

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Polyclonal

Modification

Phosphorylated

Immunogen

A synthesized peptide derived from human AKT1 around the phosphorylation site of S473

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05%BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.

引用文献

引用文献

Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats

期刊名称：

FREE RADICAL BIOLOGY AND MEDICINE

PMID：

29709706

影响因子：

6.02

应用范围：

WB,IHC

检测物种：

Rat

发表时间：

2018-04-27
Acid sphingomyelinase downregulation alleviates vascular endothelial leptin resistance in rats

期刊名称：

ACTA PHARMACOLOGICA SINICA

PMID：

31848475

影响因子：

4.01

应用范围：

WB,IHC,ICC/IF

检测物种：

Rat

发表时间：

2019-12-17
LncRNA-BC069792 suppresses tumor progression by targeting KCNQ4 in breast cancer

期刊名称：

Molecular Cancer

PMID：

36859185

影响因子：

37.3

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2023-03-01
CXCR1 drives the pathogenesis of EAE and ARDS via boosting dendritic cells-dependent inflammation

期刊名称：

Cell Death & Disease

PMID：

37709757

影响因子：

9

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-09-14
Hydroxysafflor yellow A ameliorates alcohol-induced liver injury through PI3K/Akt and STAT3/NF-κB signaling pathways

期刊名称：

PHYTOMEDICINE

PMID：

38878526

影响因子：

6.7

应用范围：

WB

检测物种：

Mouse,Human

发表时间：

2024-06-08

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CY6016

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

次日发货

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