PD L1 Ab
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PD L1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
PD L1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
PD L1 Ab
All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature.
PD L1 Ab
Western blot analysis of PD-L1 (CD274) expression in Ramos cell lysate.
PD L1 Ab
Immunohistochemical analysis of paraffin-embedded human thymoma, using PD-L1 (CD274) Antibody.
PD L1 Ab
PD L1 Ab
PD L1 Ab
PD L1 Ab
PD L1 Ab
PD L1 Ab
PD L1 Ab

产品简介

产品简介

Catalog No.

CY5980

Source

Recombinant Rabbit mAb

UniProt ID

Q9NZQ7

Reactivity

Human;Mouse;Rat

Application

WB;IHC

Calculated Mol Weight

33 kDa

Observed Mol Weight

46 kDa

Recommended Dilution

WB 1:100-1:1000

IHC 1:100-1:200

Alternative Names

B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human PD L1

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Plays a critical role in induction and maintenance of immune tolerance to self.As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response.Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10).

引用文献

引用文献

Exosomal PD-L1 functions as an immunosuppressant to promote wound healing

期刊名称：

Journal of Extracellular Vesicles

PMID：

33133428

影响因子：

11

应用范围：

WB

检测物种：

Human

发表时间：

2019-12-27
Fluvoxamine prompts the antitumor immune effect via inhibiting the PD-L1 expression on mice-burdened colon tumor

期刊名称：

CELL BIOLOGY INTERNATIONAL

PMID：

36259746

影响因子：

4.473

应用范围：

WB

检测物种：

Mouse

发表时间：

2022-10-19
High expression of circulating exosomal PD-L1 contributes to immune escape of hepatocellular carcinoma and immune clearance of chronic hepatitis B

期刊名称：

Aging-US

PMID：

39028365

影响因子：

3.9

应用范围：

IHC

检测物种：

Human

发表时间：

2024-07-17
Enzyme-Dynamic Extracellular Vesicles for Metalloimmunotherapy of Malignant Pleural Effusions

期刊名称：

ACS Nano

PMID：

39109520

影响因子：

15.8

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-08-07

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CY5980

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

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