Cyclin H Ab

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Cyclin H Ab
Western blot analysis of Cyclin H expression in HeLa cell lysate.
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab
Cyclin H Ab

产品简介

产品简介

Catalog No.

CY5833

Source

Recombinant Rabbit mAb

UniProt ID

Reactivity

Human;Mouse

Application

WB;IHC;ICC/IF;IHF;IP;FC

Calculated Mol Weight

38 kDa

Observed Mol Weight

38 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

IP 1:20-1:50

FC 1:20-1:100

Alternative Names

CAK; CCNH; CDK-activating kinase; cyclin H; cyclin-dependent kinase-activating kinase; Cyclin-H; MO15-associated protein; p34; p37;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human Cyclin H

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

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CY5833

规格:

20μl, 50μl, 100μl

价格:

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期:

现货

订购信息:

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