IRF3 Ab
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IRF3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
IRF3 Ab
Western blot analysis of IRF3 expression in (1) HeLa cell lysate; (2) 3T3 cell lysate.
IRF3 Ab
SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species. -Viral Immunology
IRF3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
IRF3 Ab
All lanes use the Antibody at 1:2K dilution for 1 hour at room temperature.
IRF3 Ab
Immunohistochemical analysis of paraffin-embedded Human Hodgkin's lymphoma, using the Antibody at 1:100 dilution.
IRF3 Ab
Immunohistochemical analysis of paraffin-embedded Human astrocytoma, using the Antibody at 1:100 dilution.
IRF3 Ab
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer, using the Antibody at 1:100 dilution.
IRF3 Ab
Immunohistochemical analysis of paraffin-embedded human cervix carcinoma, using IRF3 Antibody.
IRF3 Ab
Immunofluorescent analysis using the Antibody at 1:50 dilution.
IRF3 Ab
Immunofluorescent analysis of Jurkat cells, using IRF3 Antibody.
IRF3 Ab

产品简介

产品简介

Catalog No.

CY5779

Source

Recombinant Rabbit mAb

UniProt ID

Q14653

Reactivity

Human;Mouse;Rat

Application

WB;IHC;ICC/IF;IHF;FC

Calculated Mol Weight

47 kDa

Observed Mol Weight

50 kDa

Recommended Dilution

WB 1:1000-1:2000

IHC 1:100-1:200

ICC/IF 1:50-1:200

IHF 1:50-1:200

FC 1:20-1:100

Alternative Names

IRF3; IRF-3; IRF3; Interferon regulatory factor 3;

Host

Rabbit

Isotype

Rabbit IgG

Clonality

Monoclonal

Modification

Unmodified

Immunogen

A synthesized peptide derived from human IRF3

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Purification

Affinity-chromatography

Concentration

Buffer System

Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage Condition

Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle.

Description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses.

引用文献

引用文献

SOD2 Facilitates the Antiviral Innate Immune Response by Scavenging Reactive Oxygen Species

期刊名称：

VIRAL IMMUNOLOGY

PMID：

28574756

影响因子：

1.432

应用范围：

WB

检测物种：

Human,Mouse

发表时间：

2017-10-01
SARS-CoV-2 NSP5 and N protein counteract the RIG-I signaling pathway by suppressing the formation of stress granules

期刊名称：

Signal Transduction and Targeted Therapy

PMID：

35075101

影响因子：

38.104

应用范围：

WB

检测物种：

Human

发表时间：

2022-01-24
SARS-CoV-2 NSP8 suppresses type I and III IFN responses by modulating the RIG-I/MDA5, TRIF, and STING signaling pathways

期刊名称：

JOURNAL OF MEDICAL VIROLOGY

PMID：

36929724

影响因子：

12.7

应用范围：

WB,ICC/IF,IP

检测物种：

Human

发表时间：

2023-03-17
DLG1 promotes the antiviral innate immune response by inhibiting p62-mediated autophagic degradation of IKKε

期刊名称：

JOURNAL OF VIROLOGY

PMID：

37982618

影响因子：

5.4

应用范围：

WB

检测物种：

Mouse

发表时间：

2023-11-20
Arginine methylation-dependent cGAS stability promotes non-small cell lung cancer cell proliferation

期刊名称：

CANCER LETTERS

PMID：

38331088

影响因子：

9.1

应用范围：

WB

检测物种：

Human

发表时间：

2024-02-07
Enzyme-Dynamic Extracellular Vesicles for Metalloimmunotherapy of Malignant Pleural Effusions

期刊名称：

ACS Nano

PMID：

39109520

影响因子：

15.8

应用范围：

WB

检测物种：

Mouse

发表时间：

2024-08-07

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CY5779

规格：

20μl, 50μl, 100μl

价格：

¥600/20μl, ¥1100/50μl, ¥2000/100μl

货期：

现货

订购信息：

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